Many people like to create a drained floor for use in a shower or utility area. Attention needs to be paid to every detail of the construction if it is to be watertight. You will need to build the floor with a fall towards the drain.
Low spots are to be avoided at all costs. There should be no give in the floor whatsoever so, if you are building on timber joists and boards, it should be built with a heavier construction than a normal timber floor. The point load of an average person moving from one foot to another will cause grout lines to crack if there is any movement. Don't use chipboard or plywood less than 25mm (1in) thick.